When Gintoki apprehends a movie pirate at a premiere, he checks the camera's footage and finds himself transported to a bleak, post-apocalyptic version of Edo, where a mysterious epidemic called the "White Plague" has ravished the world's population. It turns out that the movie pirate wasn't a pirate after all—it was an android time machine, and Gintoki has been hurtled five years into the future! Shinpachi and Kagura, his Yorozuya cohorts, have had a falling out and are now battle-hardened solo vigilantes and he himself has been missing for years, disappearing without a trace after scribbling a strange message in his journal.