Betty White has passed away at age 99.

The 'Golden Girls' star passed away at her home in Los Angeles on Friday morning.

The star had a career spanning over 80 years, with the actress starting her career in 1939.

White shot to fame in the 'Mary Tyler Moore' show in the 1970s and took home 2 Emmys for her work on the show, but it was her work on the 1980's sitcom 'The Golden Girls' that cemented her place in television history.

White experienced a late-career resurgence in the 2010s after being featured in an advertisement for Snickers and was the host of 'Betty White's Off Their Rockers' which ran for 2 seasons in the 2010s.

White was a few weeks shy of celebrating her 100th birthday, and in an interview with People Magazine published in the United States this week, White cited "avoiding anything green" as the secret of her long lifespan.

Hollywood reacted to the passing of the comedy star, with Steve Martin recalling meeting the star when he was starting out in comedy.

"In 1974, I was an obscure opening act for Linda Ronstadt at the Troubadour in Los Angeles. Passing through the lobby before the show, I saw Betty White and her husband Allen Ludden waiting in line," Martin said.

He added "I loved Betty White, so I went up to them: “I’m so honoured to meet you both.” And then I said, “Isn’t Linda great?” She said, “We came to see you.” I said, “Why?” “Because we heard you were funny.” I was elated."

Henry Winkler praised White for her humour, warmth and activism, and said "it is very hard to absorb you aren't here anymore'.

The actress appeared as Ryan Reynolds' grandmother in the hit 2009 film 'The Proposal', and the films stars Sandra Bullock and Ryan Reynolds praised her work on the film.

"Timing isn't easy in comedy, because you have to navigate other people's timing - Betty pivots like I have never seen, making it look seamless" Bullock said.

Her co-star Ryan Reynolds said he was a fan of White for 'as long as he can remember' and said 'I heard that scripts for 'Golden Girls' were only 35 pages, which makes sense because so many of the laughs come from Betty simply looking at her castmates."