Pierce Brosnan's daughter has died after a three-year battle with ovarian cancer.

Charlotte, 41, whose mother Cassandra and grandmother both died from the same disease - passed away on June 28 in London where she lived with her husband Alex Smith, daughter Isabella, 14, and son Lucas, eight.

Pierce, 60, told People.com: 'On June 28 at 2 pm my darling daughter Charlotte Emily passed on to eternal life, having succumbed to ovarian cancer. She was surrounded by her husband Alex, children Isabella and Lucas and brothers Christopher and Sean. Charlotte fought her cancer with grace and humanity, courage and dignity. Our hearts are heavy with the loss of our beautiful dear girl. We pray for her and that the cure for this wretched disease will be close at hand soon. We thank everyone for their heartfelt condolences.'

Pierce adopted Charlotte and her brother Christopher, the children of Pierce's first wife Cassandra following the death of their father Dermot Harris in 1986. He and Cassandra went on to have a son Sean in 1983 before Cassandra passed away in 1991.

Pierce has been married to Keely Shaye Smith since 2001 and the couple have two children, Dylan, 16 and Paris, 12.