The iconic Irish broadcaster made the revelation on his Lyric FM show this afternoon.
He said, "I shall not be with our listeners on this day next week. Have to go to hospital this week" Adding, "They think they may have discovered a bit of cancer in the prostate and they think it may have moved up into my back."
"I've had the most wonderful, fantastic, robust, good health all my broadcasting life."
82-year-old Byrne is the original host of The Late Late Show and generally regarded as a broadcasting legend.
We wish him a speedy recovery.