The Russian national team and club teams - including the likes of CSKA Moscow and Zenit St. Petersberg - are being removed from 'FIFA'.
The move was prompted by last week's invasion of Ukraine by Russia, which EA Sports is calling for an end to.
A statement from EA Sports on Wednesday read: “EA Sports stands in solidarity with the Ukrainian people and like so many voices across the world of football, calls for peace and an end to the invasion of Ukraine."
“We will keep our communities up to date on any actions taken, and thank players for their patience as we work through these updates," the statement added.
'FIFA' possesses licences from national and club teams across the sport of football, and in a statement, EA said they were working with UEFA and FIFA (the sports governing bodies) to remove the teams from the game.
The Russian national team has already been suspended from competing in FIFA and UEFA tournaments, with this year's Champions League Final moved from the city of Saint Petersberg to Paris and Russia's World Cup play-off match against Poland also being cancelled.
The removal of anything pertaining to Russian football will apply to 'FIFA 22', 'FIFA Mobile' and 'FIFA Online', with EA adding they are "actively evaluating related changes to other areas of our games."
Russian badges, players, kits, and other Russian-themed items are a part of the Ultimate Team game mode, and players can expect to see those removed.
EA's other major sporting franchise, the 'NHL' series of games, will also remove any references to Russia in light of the situation.
The Russian invasion of Ukraine has had effects elsewhere in the entertainment world, with the planned release of 'The Batman' and Pixar's new film 'Turning Red' also halted in the country.