An obsessively cautious man, whose wife left him on their honeymoon, crosses paths with a wildly spontaneous former classmate who throws his well-ordered routine into disarray. Yet in spite of their different outlooks on life, he starts to fall for her. Romantic comedy, starring Ben Stiller, Jennifer Aniston, Debra Messing, Hank Azaria, Alec Baldwin and Philip Seymour Hoffman