Hugh Laurie was best known for playing bumbling British toffs until he reinvented his onscreen persona in the role of the curmudgeonly, charismatic House MD, and became the highest paid actor in the world. One skill that features throughout his meteoric career is a facility for music, from his beginnings with the Cambridge Footlights, to Bertie Wooster bashing out Minnie the Moocher, and House dueting with a patient. Now though, Laurie has finally put his music centre stage. As he releases an album of New Orleans blues titled Let Them Talk, he speaks with Alan Yentob about the role music has played in his life and career.