Mark Ruffalo, Julia Roberts, Taylor Kitsch, Matt Bomer and Alfred Molina star in this affecting drama that documents the rise of the HIV/AIDS epidemic in New York in the '80s, as told by the people who experienced it. Directed by Ryan Murphy - who would later go on to create American Horror Story and Glee - the film is based on the stage play of the same name, which was one of the first to address the issue as it was happening.