Andrew Graham-Dixon examines Tate Britain's new exhibition, Watercolour, Michael Smith investigates the regeneration of London's East End, and Alain de Botton trawls the BBC archive for philosophical gems. Clemency Burton-Hill looks behind the scenes of the Royal Opera House's new production about model Anna Nicole Smith, Nancy Durrant chats to artist Mary Kelly and Tom Dyckhoff travels to Miami to meet architect Frank Gehry, who discusses his next project for the New World Symphony. Mark Kermode also looks at the essential elements of sci-fi spoofs, and talks to Simon Pegg and Nick Frost about Paul, their latest addition to the genre.