A group of contenders sets out to prove that putting the words 'science' and 'nerds' into the collective team name isn't necessarily a guarantee of competence. Host Richard Ayoade watches on as they tackle four fantastical zones - Aztec, Medieval, Industrial and Futuristic. In each zone the team members must tackle physical, skill, mystery and mental challenges in a bid to win crystals. These elusive crystals each give them five seconds inside the iconic Crystal Dome, where they hope to collect gold tokens to convert into prizes.