First of a two-part documentary highlighting the difficulties faced by families who have children struggling with a range of behavioural, emotional or clinical issues. Among the children featured are a 16 year old boy with Tourette's Syndrome, whose condition appeared suddenly following a seizure, and a ten-year-old boy whose family have spent almost his entire life desperately searching for a clear, satisfactory diagnosis to help them understand why something 'is not right' with him. In episode one we meet Katherine, a lively little six year old who is the life and soul of the family at home. However, as soon as she passes through the school gates each day, she becomes mute. Unable to speak a word for eight hours a day, her family embarks on a course of intensive speech therapy to get to the cause of her resistance to talk.