Ireland host Wales at the Aviva Stadium in the first weekend of this year's Six Nations. Ireland begin their first campaign without Paul O'Connell and with both Sean O'Brien and Rob Kearney ruled out they'll be looking for leaders to step up alongside new captain Rory Best. CJ Stander is being handed his first start at Outside Flanker. The South African is the third player in this Ireland team to qualify via the three year residency rule. Wales will need no extra motivation to get one over Ireland after the manner in which they lost out on the final day of last season. (Kick Off: 3.00pm)