When you think on Dustin Hoffman's career highlights, you think of Rain Man, Marathon Man, maybe Outbreak? Kidding. Kramer Vs. Kramer is, in our book, Dustin Hoffman's greatest performance. It's also a career highlight for Meryl Streep, too. A young New York couple appear to be living an idyllic life with a young son in tow. However, feeling trapped, Streep's character decides to leave them to fend for themselves whilst Hoffman must step up as a single parent. Frequently emotional, devastatingly honest, Kramer Vs. Kramer is one of the best dramas ever made. Get some tissues.