Sabrina Grant examines why the gut is so important to a person's overall wellbeing and how it affects everything from their moods and energy, to sleep and health. Assisted by six volunteers, all with a typical gut complaint and all on a quest for a healthier gut, Sabrina puts some of the most popular regimes to the test and sees whether they actually work. Cameras observe the volunteers as they try actions including a radical bone broth diet, colonic hydrotherapy and a 10-night intense detox programme at an Ayurvedic retreat.