The journalist and former Downing Street press secretary - best known as Tony Blair's `spin doctor' during his tenure as prime minister - talks about his lifelong battle with depression. Encouraged by his family, Alastair sets out on a journey to explore if cutting-edge science can offer him, and the millions of people like him, the hope of one day living free of the illness. As he tries to better understand his depression, he also reflects on key events in his life and asks if they could have had a negative effect on his mind.