This is not the game we hoped it might be. Ireland are out of the running after their loss to Wales last week. England wrapped up the Championship with victory over Scotland, and come to Dublin looking for both the Grand Slam and the world record for most consecutive wins. Even though there are no trophies on the line, Ireland have a lot to play for including pride in the jersey and world ranking ahead of the 2019 World Cup draw.
Rob Kearney and Conor Murray are out of the squad due to injury. Jared Payne starts at fullback, returning to the team for the first time since his kidney injury. Munster's Andrew Conway is on the bench in place of Tommy Bowe, and will earn his first cap should he come on. Kieran Marmion starts, having played most of the second half last week, and Leinster's scrum half Luke McGrath comes onto the bench. After the malfunctioning line-out last week, Iain Henderson starts in place of Devin Toner. It's hoped his greater strength and physicality will help Ireland against the big Vunipola brothers.
No matter the result, the game will end with England lifting a trophy but Ireland can give them one hell of a fight.
15. Jared Payne 14. Keith Earls 13. Garry Ringrose 12. Robbie Henshaw 11. Simon Zebo 10. Johnny Sexton 9. Kieron Marmion 8. Jamie Heaslip 7. Sean O'Brien 6. CJ Stander 5. Iain Henderson 4. Devin Toner 3. Tadhg Furlong 2. Rory Best 1. Jack McGrath
16. Niall Scannell 17. Cian Healy 18. John Ryan 19. Devin Toner 20. Peter O'Mahony 21. Luke McGrath 22. Paddy Jackson 23. Andrew Conway