An intimate look at the lives and legacies of three legendary bluesmen; piano player Pinetop Perkins, drummer Willie 'Big Eyes' Smith and guitarist Hubert Sumlin, all Muddy Waters and Howlin' Wolf sidemen. The film captures some of the last interviews and final live performances, before their deaths in 2011. The historic live shows are accompanied by performances and personal insights from many of the blues and rock stars these legendary musicians inspired including; Bonnie Raitt, Gregg Allman, Derek Trucks, Susan Tedeschi, Tim Reynolds, Shemekia Copeland, Robby Krieger, Kenny Wayne Shepherd, Joe Perry, Joe Bonamassa and Johnny Winter.