The film comprises Sarah Silverman's performance before a live audience interwoven with stylish musical numbers and backstage intrigue. Comedians Bob Odenkirk and Brian Posehn also make appearances along with Silverman's band, The Silver Men. Known as one of the funniest and most provocative people in comedy, Silverman has been compared to the legendary Lenny Bruce. Despite the current political climate, she takes on such pitch-black topics as September 11th, unwanted body hair and the Holocaust and spins them into decidedly un-PC comedic gold.