It should be the happiest time in Valeria’s life. She and her husband, Raul, have finally seen one of their longtime dreams come true: Valeria is pregnant. At first, everything seems perfect. Gradually, though, her mood darkens. With motherhood upon her, Valeria can't shake off heavy self-doubt and a pervasive dread, the latter stemming from visions of spider-like presences and other possibly supernatural threats, all of which may be the work of an entity known as “La Huesera.” Hoping to confront these demons, she reconnects with the old, more carefree life she once gave up for Raul, including rekindling an old flame with her first love, Octavia.