Juan Campos (Arath de la Torre) has dedicated his life to seducing the most beautiful women with his friend and accomplice, Luis Pani. When they prepare for their trip to the Dominican Republic, Luis falls ill, and Juan is forced to take his nephew Mau (Jesus Zavala), a 20 year old boy who is going through the depression of losing his first love. While Juan trains Mau in the art of seduction, Teresa D'Ors (Marina de Tavira) appears, the only woman in the world capable of paralyzing Juan. Together, they venture on a journey where they will learn from each other and discover that in love nothing is certain.