The story of roguish Huey and nebbishy Bernard, who are unlikely collegiate friends in late 1980s New York. Years later, a bedraggled Huey crashes at Bernard's upscale bachelor pad. As the two reconnect, Bernard falls in love with Huey's estranged daughter Zelda, an aspiring graphic novelist who's got a seductive new creative partner, Conrad. Huey slowly gets his mojo back and tries to seduce the various women in Bernard's life, including his off-again girlfriend Roz and colleague, Mona, while reconnecting with his ex-wife and brother.