21 Grams

A couple of years ago, Mexican director Alejandro Gonzalez Inarritu made an excellent film about destiny called Amores Perros, which interlinked three stories around an accident. He repeats that trick with his English language debut, the superb 21 Grams, a film skewered in its narrative, but one that pushes its cast towards some of their most brilliant work. In this gripping but unusually structured film, Penn plays a mathematician who is slowly dying from heart disease and desperately requires a transplant.