Ever since hulking lawman Hobbs (Johnson), a loyal agent of America's Diplomatic Security Service, and lawless outcast Shaw (Statham), a former British military elite operative, first faced off, the duo have swapped smack talk and body blows as they've tried to take each other down. But when cyber-genetically enhanced anarchist Brixton (Idris Elba) gains control of an insidious bio-threat that could alter humanity forever, these two sworn enemies will have to partner up to bring down the only guy who might be badder than themselves.