Rose Byrne and Bobby Cannavale are doing a Rachel Weitz/Daniel Craig. The real life lovebirds are to play hubby and wife in a new comedy drama called Brother's Keeper from the producer of indie fave Lost in Translation.

According to The Hollywood Reporter, the finest looking couple in the land will join Nick Kroll (who is best known for appearing in US comedy series The League but who you might recognise from his role as The Douche in Parks and Recreation) in the flick about a cocky entrepreneur who has a mental breakdown on his new company's launch night. After abandoning his life in Manhattan he moves in with his sister and brother-in-law and ends up becoming his nephew's babysitter.

Rose Byrne is a favourite round these parts and we already know she can do comedy thanks to her star turn in Bridesmaids and Bobby Cannavale won an Emmy this year for his work on Boardwalk Empire. They definitely look good on each others arms on the red carpet; we are looking forward to seeing how their red-hot chemistry translates on film.