Safe to say that Twitter had a field day with "Firstly, are you okay?"
The whole 'This Morning' saga has dominated tabloid headlines for weeks now, but just as it appeared to be running out of steam, Holly Willoughby's return has breathed new life into it.
Willoughby's first show without her usual co-host Philip Schofield (who has left the show and ITV, in case you've been living under a rock) took place yesterday morning, when she returned from her half-term exile.
However, the serious tone that Willoughby chose to make her opening statement with - as well as her opening line, asking viewers "Firstly, are you okay? I hope so" - has led to some serious lampooning on social media.
Willoughby went on to say how she felt "shaken, troubled, let down" and "worried for the wellbeing of people on all sides of what's been going on" after Schofield left the show following the revelation that he had had what he described as an "unwise, but not illegal" relationship with a younger colleague.
Her speech has inspired a multitude of memes and a generally amusing reaction amongst Twitter users - see the best of them below...