The actress who played the role of Howard's mother has passed away at the age of 62. Carol Ann Susi was actually never seen on screen in the show but fans will know her voice and that distinctive Brooklyn accent that went with it.

The actress had appeared in numerous other film and TV shows too including Coyote Ugly, Becker, Grey's Anatomy, That '70s Show and Married with Children. She passed away following a brief battle with an aggressive form of cancer.

Big Bang Theory producers Chuck Lorre, Steve Molaro and Bill Prady paid tribute to the actress in a statement; "The Big Bang Theory family has lost a beloved member today with the passing of Carol Ann Susi, who hilariously and memorably voiced the role of Mrs Wolowitz."

"Unseen by viewers, the Mrs Wolowitz character became a bit of a mystery throughout the show's eight seasons. What was not a mystery, however, was Carol Ann's immense talent and comedic timing, which were on display during each unforgettable appearance."

"In addition to her talent, Carol Ann was a constant source of joy and kindness to all. Our thoughts and deepest condolences are with her family during this time, and we will miss her greatly."

Actor Kunal Nayyar, who plays Howard on the show, also paid tribute to the actress;

Here Howard's mom in action...